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MEDICAL DICTIONARY


Whipple disease: A form of intestinal malabsorption (an inability to absorb nutrients from the intestine) described in 1907 by the pathologist and Nobel laureate George H. Whipple in a medical missionary who first developed arthritis and then weight loss, cough, fever , diarrhea , hypotension ( low blood pressure ), abdominal swelling, increased skin pigmentation, and severe anemia .

The disease has been discovered to be due to a previously unknown type of bacteria, now named Tropheryma whippelii, which was reported in the year 2000 to have been grown in the laboratory, opening the way for the development of a simple blood test to diagnose the disease. It is treated with antibiotics. Some patients relapse and need long-term, even life-long, treatment.

 

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