MEDICAL DICTIONARY
Retinoic acid syndrome: A syndrome that occurs from treatment with retinoic acid and is characterized by fever , dyspnea (difficulty breathing), chest pain, lung infiltrates evident on chest X-ray , pleural and pericardial effusions (fluid around the lungs and heart ) and hypoxia (lack of oxygen ).
The syndrome occurs within the first 3 weeks of retinoic acid treatment, for example, with the drug ATRA (all-trans retinoic acid) used in treating APL acute promyelocytic leukemia ).
The retinoic acid syndrome involves the adhesion (sticking) of malignant cells in the pulmonary blood vessels. Steroids, chemotherapy , and supportive measures can help. The syndrome is a very serious complication. About 10% of patients with the syndrome die of it.
|
DISCLAIMER:
Information on this site is provided for informational
purposes and is not meant to substitute for the advice
provided by your own physician or other medical professional.
You should not use the information contained herein
for diagnosing or treating a health problem or disease,
or prescribing any medication. You should read carefully
all product packaging. Not all Canadian drugs, Canada
prescription and Canadian prescription medicine is available
at discount Canadian on line pharmacies. If you have
or suspect that you have a medical problem, promptly
contact your health care provider. Information and statements
regarding diet supplements have not been evaluated by
Health Canada and are not intended to diagnose, treat,
cure, or prevent any disease. All trade and service
marks mentioned on this site are recognized as belonging
to their respective owners.
|
|
|
|
