MEDICAL DICTIONARY
Lamin A: Abbreviated LMNA. A gene on chromosome 1 that encodes a protein which is a key component of the membrane surrounding the cell nucleus. Mutations in the LMNA gene are responsible for a number of genetic disorders including: - Progeria syndrome ,
- Emery-Dreifuss muscular dystrophy type 2,
- Limb girdle muscular dystrophy type 1B,
- Charcot-Marie-Tooth disorder type 2B1,
- The Dunnigan type of familial partial lipodystrophy ,
- Mandibuloacral dysplasia and
- A familial form of dilated cardiomyopathy .
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