MEDICAL DICTIONARY
Gene, Y-linked: A gene on the Y chromosome .
(Y-linkage is analogous to X-linkage (the presence of a gene on the X chromosome ) in that it says a gene is on one of the sex chromosomes.)
It has often been said that little is known about genes that may be Y-linked. This is no longer true. As of the year 2000, a number of genes were known to be Y-linked including: - ASMTY (which stands for acetylserotonin methyltransferase),
- TSPY (testis-specific protein ),
- IL3RAY ( interleukin-3 receptor ),
- SRY (sex-determining region),
- TDF ( testis determining factor),
- ZFY ( zinc finger protein), PRKY (protein kinase, Y-linked),
- AMGL (amelogenin),
- CSF2RY (granulocyte-macrophage colony-stimulating factor receptor, alpha subunit on the Y chromosome),
- ANT3Y ( adenine nucleotide translocator-3 on the Y),
- AZF2 (azoospermia factor 2),
- BPY2 (basic protein on the Y chromosome),
- AZF1 (azoospermia factor 1),
- DAZ (deleted in azoospermia),
- RBM1 ( RNA binding motif protein, Y chromosome, family 1, member A1),
- RBM2 (RNA binding motif protein 2) and
- UTY (ubiquitously transcribed TPR gene on Y chromosome).
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