MEDICAL DICTIONARY
Carcinogen: A substance or agent that causes cancer. Related terms include the adjective " carcinogenic " and the nouns "carcinogenesis" and "carcinogenicity." One of the best-known carcinogens is ionizing radiation.
The International Agency for Research on Cancer has classified some 60 substances and processes as probably or definitely carcinogenic in humans. These substances and processes are divided into three categories -- Agents and groups of agents, Mixtures, and Exposure circumstances -- and they are as follows:
Agents and groups of agents
Aflatoxins, naturally occurring 4-Aminobiphenyl Arsenic and arsenic compounds Asbestos Azathioprine Benzene Benzidine Beryllium and beryllium compounds N,N-Bis(2-chloroethyl)-2-naphthylamine (chlornaphazine) Bis(chloromethyl) ether and chloromethyl methyl ether 1,4-Butanediol dimethanesulfonate (busulfan; Myleran) Cadmium and cadmium compounds Chlorambucil 1-(2-Chloroethyl)-3-(4-methylcyclohexyl)-1-nitrosourea (methyl-CCNU; Semustine) Chromium [VI] compounds Cyclosporine Cyclophosphamide Diethylstilbestrol Erionite Ethylene oxide Melphalan Methoxypsoralen (methoxsalen) plus ultraviolet radiation MOPP and other combined chemotherapy including alkylating agents Mustard gas (sulfur mustard) 2-Naphthylamine Nickel compounds Estrogen therapy , postmenopausal Radon and its decay products Silica , crystalline Solar radiation Talc-containing asbestiform fibers 2,3,7,8-Tetrachlorodibenzo-para-dioxin Thiotepa Treosulfan Vinyl chloride
Mixtures
Alcoholic beverages Analgesic mixtures containing phenacetin Betel quid with tobacco Coal-tar pitches Coal tars Mineral oils, untreated and mildly treated Salted fish (Chinese style) Shale oils Soots Tobacco products, smokeless Tobacco smoke Wood dust
Exposure circumstances
Aluminum production Auramine manufacturing Boot and shoe manufacture and repair Coal gasification Coke production Furniture and cabinet making Hematite mining (underground) with exposure to radon Iron and steel founding Isopropanol manufacturing (strong-acid process) Magenta manufacturing Painting (occupational exposure) Rubber industry Strong-inorganic-acid mists containing sulfuric acid (occupational exposure)
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